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Studies designed to provide insight into clinical practice in the real world are known as pragmatic trials. They are typically focused on the practical aspects of the study design, including the recruitment and consent process as well as adherence to the use of routinely available equipment.
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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which used a variety of investigators and participants from different geographic areas. This type of heterogeneity, that is crucial for a pragmatic trial to be valid and lessen the chance of bias is also essential. However too much heterogeneity could result in problems with the design of the trial.
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Pragmatic trials are designed to replicate real-world situations and have the highest external validity. They are usually requested by policy makers and practitioners to guide their decision-making. They can also be used to determine the causality of an intervention and its results. However, they should not, be used to replace the need for explanation studies.
The pragmatism idea is controversial and 프라그마틱 정품 사이트 [Https://Coolpot.Stream/Story.Php?Title=20-Pragmatic-Free-Trial-Websites-Taking-The-Internet-By-Storm-8] there are questions about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 proposed an distinction between explanation-based studies, which prove the validity of a physiological or clinical hypothesis, as well as pragmatic trials, which inform policy and practice decision-making. They also suggested an approach to pragmatic trials, called PRECIS.2 This tool was designed to define the features of a practical trial, including the recruitment process, the design and implementation of the intervention, and monitoring.
There is a positive increase in the number pragmatic trials that have been published. A recent Medline search using the keywords pragmatic and naturalistic, restricted to controlled trials that are randomized (RCTs) produced 34 articles, shown in red in Figure 2. This suggests that the health sciences community has become more aware of the importance of pragmatism. It is important to keep in mind that the majority of studies were conducted in primary-care settings.